Myocarditis (peds): Difference between revisions
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''This page is for <u>pediatric</u> patients; for adult patients see [[myocarditis]].'' | ''This page is for <u>pediatric</u> patients; for adult patients see [[myocarditis]].'' | ||
==Background== | ==Background== | ||
*Rare but potentially fatal | |||
*Most common cause of heart failure in previously healthy children | |||
*Inflammation of myocardium | |||
**Can lead to dilated [[cardiomyopathy]] | |||
*Typically [[viruses|viral]] but often no pathogen identified | |||
==Clinical Features== | ==Clinical Features== | ||
*Symptoms often initially nonspecific in prodromal stage, may be misdiagnosed as [[URI]], [[pneumonia]], [[acute gastroenteritis (peds)|gastroenteritis]], [[asthma]] | |||
*Prodrome typically lasts ~7 days | |||
*Most common presenting symptoms include <ref>Freedman SB1, Haladyn JK, Floh A, Kirsh JA, Taylor G, Thull-Freedman J. Pediatric myocarditis: emergency department clinical findings and diagnostic evaluation. Pediatrics. 2007 Dec;120(6):1278-85.</ref> | |||
**[[Shortness of breath (peds)|Shortness of breath]] | |||
**[[Fever]] | |||
**[[URI]] symptoms | |||
**[[Vomiting]] or [[abdominal pain (peds)|abdominal pain]] | |||
**Poor feeding | |||
**Hypoperfusion (e.g. [[syncope]] or [[seizure (peds)|seizure]] | |||
**+/- [[chest pain]], [[palpitations]]<ref>Dancea AB. Myocarditis in infants and children: A review for the paediatrician. Paediatr Child Health. 2001;6(8):543–545. doi:10.1093/pch/6.8.543</ref> | |||
*Exam findings include<ref>Durani Y1, Egan M, Baffa J, Selbst SM, Nager AL. Pediatric myocarditis: presenting clinical characteristics. Am J Emerg Med. 2009 Oct;27(8):942-7.</ref> | |||
**[[Tachycardia]] | |||
***Consider myocarditis in any child who remains persistently tachycardic despite appropriate treatment for fever, dehydration, etc. | |||
***Only present in 46-58% of cases in 3 large reviews<ref>Durani Y1, Egan M, Baffa J, Selbst SM, Nager AL. Pediatric myocarditis: presenting clinical characteristics. Am J Emerg Med. 2009 Oct;27(8):942-7.</ref><ref>Freedman SB1, Haladyn JK, Floh A, Kirsh JA, Taylor G, Thull-Freedman J. Pediatric myocarditis: emergency department clinical findings and diagnostic evaluation. Pediatrics. 2007 Dec;120(6):1278-85.</ref><ref>Shu-Ling C1, Bautista D, Kit CC, Su-Yin AA. Diagnostic evaluation of pediatric myocarditis in the emergency department: a 10-year case series in the Asian population. Pediatr Emerg Care. 2013 Mar;29(3):346-51.</ref>, so ''lack'' of tachycardia does ''not'' rule out myocarditis | |||
**[[Fever]] | |||
**[[Respiratory distress]], tachypnea | |||
**[[Hepatomegaly]] | |||
**Signs of poor perfusion (e.g. decreased cap refill, mottled skin) | |||
**[[Altered mental status (peds)|Lethargy]] | |||
==Differential Diagnosis== | ==Differential Diagnosis== | ||
| Line 10: | Line 31: | ||
==Evaluation== | ==Evaluation== | ||
*[[ECG]] | |||
**[[Sinus tachycardia]] is most common abnormality | |||
**Other abnormalities includes<ref>Freedman SB1, Haladyn JK, Floh A, Kirsh JA, Taylor G, Thull-Freedman J. Pediatric myocarditis: emergency department clinical findings and diagnostic evaluation. Pediatrics. 2007 Dec;120(6):1278-85.</ref> | |||
**Large voltage | |||
**Axis deviation | |||
**ST or [[T wave changes]] | |||
**[[AV blocks]] | |||
**[[myocardial ischemia|Ischemic]] patterns | |||
*[[CXR]] | |||
**Not sensitive, but often abnormal<ref>Durani Y1, Egan M, Baffa J, Selbst SM, Nager AL. Pediatric myocarditis: presenting clinical characteristics. Am J Emerg Med. 2009 Oct;27(8):942-7.</ref> | |||
**Cardiomegaly | |||
**[[Pulmonary edema]] | |||
**[[Pleural effusions]] | |||
*[[Echocardiography]] | |||
**Unnecessary if both CXR and ECG are normal, unless you have high clinical suspicion | |||
*Elevated [[LFTs]], [[troponin]] in many cases<ref>Eisenberg MA1, Green-Hopkins I, Alexander ME, Chiang VW. Cardiac troponin T as a screening test for myocarditis in children</ref> | |||
==Management== | ==Management== | ||
*Management tailored to severity of disease | |||
*Maintain euvolemia, [[diuretics]] as needed | |||
*If cardiac function significantly depressed, consider [[dopamine]] or [[dobutamine]] | |||
*Consider afterload reduction with [[nitroprusside]] if normotensive | |||
*Treat [[arrhythmias]] | |||
**Avoid digoxin due to risk of precipitating more significant dysrhythmias in irritable myocardium | |||
==Disposition== | ==Disposition== | ||
*Admit, often to ICU | |||
==See Also== | ==See Also== | ||
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==External Links== | ==External Links== | ||
*https://pedemmorsels.com/myocarditis/ | |||
==References== | ==References== | ||
Revision as of 15:00, 23 October 2019
This page is for pediatric patients; for adult patients see myocarditis.
Background
- Rare but potentially fatal
- Most common cause of heart failure in previously healthy children
- Inflammation of myocardium
- Can lead to dilated cardiomyopathy
- Typically viral but often no pathogen identified
Clinical Features
- Symptoms often initially nonspecific in prodromal stage, may be misdiagnosed as URI, pneumonia, gastroenteritis, asthma
- Prodrome typically lasts ~7 days
- Most common presenting symptoms include [1]
- Shortness of breath
- Fever
- URI symptoms
- Vomiting or abdominal pain
- Poor feeding
- Hypoperfusion (e.g. syncope or seizure
- +/- chest pain, palpitations[2]
- Exam findings include[3]
- Tachycardia
- Fever
- Respiratory distress, tachypnea
- Hepatomegaly
- Signs of poor perfusion (e.g. decreased cap refill, mottled skin)
- Lethargy
Differential Diagnosis
Pediatric Shortness of Breath
Pulmonary/airway
- Airway obstruction
- Structural
- Infectious
- Other
Cardiac
- Congenital heart disease
- Vascular ring
- Cardiac tamponade
- Congestive Heart Failure (peds)
- Myocarditis (peds)
Other diseases with abnormal respiration
- Normal neonatal periodic breathing (misinterpreted by caregivers as abnormal)
- Brief resolved unexplained event
- Anemia
- Abdominal distension (e.g. SBO, liver failure
- Neonatal abstinence syndrome
- Decreased perfusion states
- Metabolic acidosis
- CO Poisoning
- Diaphragm injury
- Renal Failure
- Electrolyte abnormalities
- Organophosphate toxicity
- Tick paralysis
- Fever (Peds)
- Panic attack
- Porphyria
Evaluation
- ECG
- Sinus tachycardia is most common abnormality
- Other abnormalities includes[7]
- Large voltage
- Axis deviation
- ST or T wave changes
- AV blocks
- Ischemic patterns
- CXR
- Not sensitive, but often abnormal[8]
- Cardiomegaly
- Pulmonary edema
- Pleural effusions
- Echocardiography
- Unnecessary if both CXR and ECG are normal, unless you have high clinical suspicion
- Elevated LFTs, troponin in many cases[9]
Management
- Management tailored to severity of disease
- Maintain euvolemia, diuretics as needed
- If cardiac function significantly depressed, consider dopamine or dobutamine
- Consider afterload reduction with nitroprusside if normotensive
- Treat arrhythmias
- Avoid digoxin due to risk of precipitating more significant dysrhythmias in irritable myocardium
Disposition
- Admit, often to ICU
See Also
External Links
References
- ↑ Freedman SB1, Haladyn JK, Floh A, Kirsh JA, Taylor G, Thull-Freedman J. Pediatric myocarditis: emergency department clinical findings and diagnostic evaluation. Pediatrics. 2007 Dec;120(6):1278-85.
- ↑ Dancea AB. Myocarditis in infants and children: A review for the paediatrician. Paediatr Child Health. 2001;6(8):543–545. doi:10.1093/pch/6.8.543
- ↑ Durani Y1, Egan M, Baffa J, Selbst SM, Nager AL. Pediatric myocarditis: presenting clinical characteristics. Am J Emerg Med. 2009 Oct;27(8):942-7.
- ↑ Durani Y1, Egan M, Baffa J, Selbst SM, Nager AL. Pediatric myocarditis: presenting clinical characteristics. Am J Emerg Med. 2009 Oct;27(8):942-7.
- ↑ Freedman SB1, Haladyn JK, Floh A, Kirsh JA, Taylor G, Thull-Freedman J. Pediatric myocarditis: emergency department clinical findings and diagnostic evaluation. Pediatrics. 2007 Dec;120(6):1278-85.
- ↑ Shu-Ling C1, Bautista D, Kit CC, Su-Yin AA. Diagnostic evaluation of pediatric myocarditis in the emergency department: a 10-year case series in the Asian population. Pediatr Emerg Care. 2013 Mar;29(3):346-51.
- ↑ Freedman SB1, Haladyn JK, Floh A, Kirsh JA, Taylor G, Thull-Freedman J. Pediatric myocarditis: emergency department clinical findings and diagnostic evaluation. Pediatrics. 2007 Dec;120(6):1278-85.
- ↑ Durani Y1, Egan M, Baffa J, Selbst SM, Nager AL. Pediatric myocarditis: presenting clinical characteristics. Am J Emerg Med. 2009 Oct;27(8):942-7.
- ↑ Eisenberg MA1, Green-Hopkins I, Alexander ME, Chiang VW. Cardiac troponin T as a screening test for myocarditis in children
