Capnocytophaga canimorsus

Background

• Gram negative organism ransmitted through dog bites
• Risk factors:
  • Splenectomy
  • Hyposplenism
  • Alcoholism
• Presents commonly as septic shock, multiorgan system failure, gangrene, meningitis
• Supportive therapy, antibiotics
• Mortality 26-30%

Antibiotic Sensitivities

• Penicillin G
• Augmentin
• Carbapenema

Key

• S susceptible/sensitive (usually)
• I intermediate (variably susceptible/resistant)
• R resistant (or not effective clinically)
• S+ synergistic with cell wall antibiotics
• U sensitive for UTI only (non systemic infection)
• X1 no data
• X2 active in vitro, but not used clinically
• X3 active in vitro, but not clinically effective for Group A strep pharyngitis or infections due to E. faecalis
• X4 active in vitro, but not clinically effective for strep pneumonia

See Also

• Microbiology (Main)
• Mammalian Bites

References

• EBMedicine