Ciprofloxacin: Difference between revisions
Line 40: | Line 40: | ||
===[[Salmonella]]=== | ===[[Salmonella]]=== | ||
*''Acute''' | *'''Acute''' | ||
**500-750mg PO q12h x 3-7 days | **500-750mg PO q12h x 3-7 days | ||
***Extend treatment x 1 week if immunocompromised | ***Extend treatment x 1 week if immunocompromised |
Revision as of 03:27, 19 March 2014
General
- Type: Fluoroquinolones
- Dosage Forms: IV; PO (Standard: 100, 250, 500; ER 500, 1000)
- Common Trade Names: Cipro
Adult Dosing
General
- PO
- 250-750mg PO q12h
- First Dose: 250-750mg PO x1
- IV
- 200-400mg IV q12
- First Dose: 400mg IV x 1
- Alt: 400mg IV q8h
UTI
- Uncomplicated
- 500mg ER PO q24h x 3 days
- Alt: 250mg PO q12h x 3 days
- Complicated
- IV: 400mg IV q12h x 7-14 days
- PO: 1000mg ER PO q24h x 7-14 days
- Alt: 500mg PO q12h x 7-14 days
Anthrax
- Inhalational, Gi, oropharyngeal
- 400mg IV q12h OR 500mg PO q12 x 60 days
- First dose: 400mg IV + 1-2 additional antibiotics
- Cutaneous
- 400mg IV q12h OR 500mg PO q12 x 7-10 days
- Info: Give x 60 days if bioterrorism suspected
- 400mg IV q12h OR 500mg PO q12 x 7-10 days
- Post-Exposure Prophylaxis
- 500mg PO q12h x 60 days (or exposure excluded)
Typhoid Fever
- 500mg PO q12h x 2 weeks
Chancroid
- 500mg PO q12h x 3 days
Salmonella
- Acute
- 500-750mg PO q12h x 3-7 days
- Extend treatment x 1 week if immunocompromised
- 500-750mg PO q12h x 3-7 days
- Chronic Carrier
- 750mg PO q12h x 1 month
Pediatric Dosing
Special Populations
- Pregnancy: C (but indicated for anthrax)
- Lactation: Probably safe
- Renal Dosing
- Adult
- Pediatric
- Hepatic Dosing
- Adult
- Pediatric
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
Common
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
- Mechanism of Action: