Glycopeptide

Adverse Effects

• Red Man Syndrome: Flushing, rash, itching, hypotension during IV infusion; prevent with slow infusion.
• Nephrotoxicity: Kidney damage, especially with high doses or concurrent nephrotoxic drugs; monitor renal function.
• Ototoxicity: Hearing loss or tinnitus, more common with high levels or prolonged use.
• Hematologic Effects: Neutropenia, thrombocytopenia, or anemia; usually reversible.
• Hypersensitivity Reactions: Rash, fever, or severe reactions like Stevens-Johnson syndrome.
• Gastrointestinal Issues: Nausea, vomiting, diarrhea (more with oral use).
• Other: Phlebitis, elevated liver enzymes, or superinfections.

List of Glycopeptides

• Teicoplanin
• Vancomycin