Vitamin A deficiency

Background

  • One of the most common vitamin deficiencies in developing countries
  • Most common cause of blindness in developing world
  • In US, most commonly found in conjunction with fat malabsorption syndromes (e.g. IBD, pancreatic insufficiency, sprue, cystic fibrosis, laxative abuse)

Clinical Features

Differential Diagnosis

Acute Vision Loss (Noninflamed)

Emergent Diagnosis

Vitamin deficiencies

Evaluation

  • Eye exam
  • Serum Vitamin A level below 30–65 mg/dL

Management

  • Early: vitamin A 30,000 IU PO daily x 1 week
  • Advanced: vitamin A 20,000 IU/kg PO daily for at least 5 days

Disposition

See Also

External Links

References

Authors:

Claire