User:Danbot/MedicationDose Sandbox: Difference between revisions

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==Proof of Concept: MedicationDose on RSI==
==MedicationDose System — Live Demo==
''This is a demonstration of how {{tl|MedicationDose}} would look on the RSI page.''
''This page demonstrates the {{tl|MedicationDose}} SMW system. All data below is dynamically queried from the actual disease/procedure pages.''


===Premedication===
===All Medications by Indication===
*{{MedicationDose|drug=Lidocaine|dose=1.5 mg/kg|route=IV|context=Premedication|indication=Rapid sequence intubation|population=Adult|notes=May lower ICP; give 5-10 min prior}}
{{#ask:[[Has Indication::+]][[Has DrugName::+]]
*{{MedicationDose|drug=Fentanyl|dose=3 mcg/kg|route=IV|context=Premedication|indication=Rapid sequence intubation|population=Adult|notes=Blunts sympathetic response; give last}}
|?Has DrugName=Drug
|?Has Dose=Dose
|?Has Indication=Indication
|?Has Context=Context
|?Has Population=Population
|?Has Route=Route
|format=broadtable
|headers=plain
|sort=Has Indication,Has Context,Has DrugName
|limit=150
}}


===Induction===
===Example: Drug Page Query — All Indications for Ketamine===
*{{MedicationDose|drug=Etomidate|dose=0.2-0.4 mg/kg|route=IV|context=Induction|indication=Rapid sequence intubation|population=Adult|onset=1 min|duration=3-8 min|notes=Hemodynamically neutral}}
{{#ask:[[Has DrugName::Ketamine]]
*{{MedicationDose|drug=Ketamine|dose=1-2 mg/kg|route=IV|context=Induction|indication=Rapid sequence intubation|population=Adult|onset=1 min|duration=10-20 min|notes=Agent of choice for asthmatics and hypotension}}
|?Has Indication=Indication
*{{MedicationDose|drug=Ketamine|dose=3-4 mg/kg|route=IM|context=Induction (IM)|indication=Rapid sequence intubation|population=Adult|onset=3-4 min|duration=10-20 min}}
|?Has Dose=Dose
*{{MedicationDose|drug=Midazolam|dose=0.2-0.3 mg/kg|route=IV|context=Induction|indication=Rapid sequence intubation|population=Adult|display=Versed|onset=1-2 min|duration=30-60 min}}
|?Has Context=Context
*{{MedicationDose|drug=Propofol|dose=1-3 mg/kg|route=IV|context=Induction|indication=Rapid sequence intubation|population=Adult|onset=<1 min|duration=10-15 min}}
|?Has Route=Route
 
|?Has Population=Population
===Paralytics===
|format=broadtable
*{{MedicationDose|drug=Succinylcholine|dose=1.5 mg/kg|route=IV|context=Paralytic|indication=Rapid sequence intubation|population=Adult|onset=45 sec|duration=4-6 min}}
|headers=plain
*{{MedicationDose|drug=Succinylcholine|dose=2.0 mg/kg|route=IV|context=Paralytic|indication=Rapid sequence intubation|population=Pediatric|onset=45 sec|duration=4-6 min|notes=Age < 10 years}}
|sort=Has Indication
*{{MedicationDose|drug=Succinylcholine|dose=4 mg/kg|route=IM|context=Paralytic (IM)|indication=Rapid sequence intubation|population=Adult|onset=2-3 min|duration=10-30 min}}
}}
*{{MedicationDose|drug=Rocuronium|dose=1.2 mg/kg|route=IV|context=Paralytic (RSI dose)|indication=Rapid sequence intubation|population=Adult|onset=60 sec|duration=25-60 min}}
*{{MedicationDose|drug=Vecuronium|dose=0.1 mg/kg|route=IV|context=Paralytic|indication=Rapid sequence intubation|population=Adult|onset=60-90 sec|duration=65 min|notes=Agent of choice for prolonged paralysis}}
 
===Post-intubation Sedation===
*{{MedicationDose|drug=Propofol|dose=5-80 mcg/kg/min|route=IV drip|context=Post-intubation sedation|indication=Rapid sequence intubation|population=Adult|notes=Titrate q10min}}
*{{MedicationDose|drug=Fentanyl|dose=25-250 mcg/hr|route=IV drip|context=Post-intubation analgesia|indication=Rapid sequence intubation|population=Adult|notes=Titrate q20min}}
*{{MedicationDose|drug=Midazolam|dose=0.04-0.2 mg/kg/hr|route=IV drip|context=Post-intubation sedation|indication=Rapid sequence intubation|population=Adult|display=Versed|notes=Titrate q1hr}}


==SMW Query Demo: All RSI Medications==
===Example: Drug Page Query — All Indications for Epinephrine===
{{#ask:[[Has Indication::Rapid sequence intubation]]
{{#ask:[[Has DrugName::Epinephrine]]
  |?Has DrugName=Drug
  |?Has Indication=Indication
  |?Has Dose=Dose
  |?Has Dose=Dose
  |?Has Context=Context
  |?Has Context=Context
|?Has Population=Population
  |?Has Route=Route
  |?Has Route=Route
|?Has Onset=Onset
|?Has Duration=Duration
  |format=broadtable
  |format=broadtable
  |headers=plain
  |headers=plain
  |sort=Has Context,Has DrugName
  |sort=Has Indication
|limit=50
}}
}}


[[Category:Sandbox]]
[[Category:Sandbox]]

Revision as of 15:58, 20 March 2026

MedicationDose System — Live Demo

This page demonstrates the {{MedicationDose}} SMW system. All data below is dynamically queried from the actual disease/procedure pages.

All Medications by Indication

 DrugDoseIndicationContextPopulationRoute
Acute allergic reaction#Methylprednisolone Corticosteroid AdultMethylprednisolone125mgAcute allergic reactionCorticosteroidAdultIV/IM
Acute allergic reaction#Prednisone Corticosteroid (outpatient) AdultPrednisone60mg initially, then 40mg PO daily x 5 daysAcute allergic reactionCorticosteroid (outpatient)AdultPO
Acute allergic reaction#Diphenhydramine H1 antagonist AdultDiphenhydramine50mgAcute allergic reactionH1 antagonistAdultIV/IM/PO
Acute allergic reaction#Cetirizine H1 antagonist; less sedating alternative AdultCetirizine10mgAcute allergic reactionH1 antagonist; less sedating alternativeAdultIV/PO
Acute allergic reaction#Cetirizine H1 antagonist; less sedating alternative PediatricCetirizine5-10mg IV (6-11yo); 2.5mg IV (6mo-5yo)Acute allergic reactionH1 antagonist; less sedating alternativePediatricIV
Acute allergic reaction#Famotidine H2 antagonist; improves urticaria AdultFamotidine40mgAcute allergic reactionH2 antagonist; improves urticariaAdultIV/IM/PO
Acute arterial ischemia#Unfractionated heparin Anticoagulation to prevent clot propagation AdultUnfractionated heparin80 units/kg bolus, then 18 units/kg/hr infusionAcute arterial ischemiaAnticoagulation to prevent clot propagationAdultIV
Acute asthma exacerbation#Magnesium sulfate Adjunct for moderate-severe asthma AdultMagnesium sulfate25-75 mg/kg IV over 30 min (2-3 g in most adults)Acute asthma exacerbationAdjunct for moderate-severe asthmaAdultIV
Acute asthma exacerbation#Ipratropium Anticholinergic adjunct (acute setting only) AdultIpratropium0.25-0.5 mg nebulized q20min x2-3 dosesAcute asthma exacerbationAnticholinergic adjunct (acute setting only)AdultNebulized
Acute asthma exacerbation#Terbutaline Beta-2 agonist (longer-acting) AdultTerbutaline0.25 mg SC/IM q20min x3Acute asthma exacerbationBeta-2 agonist (longer-acting)AdultSC/IM
Acute asthma exacerbation#Albuterol Bronchodilator (1st line) AdultAlbuterol2.5-5 mg nebulized q20min x3, then 2.5-10 mg q1-4hr PRN; or continuous 0.5 mg/kg/hr (max 15 mg/hr)Acute asthma exacerbationBronchodilator (1st line)AdultNebulized
Acute asthma exacerbation#Albuterol Bronchodilator (MDI alternative) AdultAlbuterol6-12 puffs MDI q20min up to 4h, then q1-4hr PRNAcute asthma exacerbationBronchodilator (MDI alternative)AdultMDI
Acute asthma exacerbation#Albuterol Bronchodilator (pediatric) PediatricAlbuterol0.15 mg/kg (min 2.5 mg) nebulized q20min x3, then 0.15-0.3 mg/kg q1-4h PRN; or continuous 0.5 mg/kg/hrAcute asthma exacerbationBronchodilator (pediatric)PediatricNebulized
Acute asthma exacerbation#Prednisone Corticosteroid AdultPrednisone40-60 mg PO daily x5 daysAcute asthma exacerbationCorticosteroidAdultPO
Acute asthma exacerbation#Methylprednisolone Corticosteroid (if unable to tolerate PO) AdultMethylprednisolone1 mg/kg IV q4-6hAcute asthma exacerbationCorticosteroid (if unable to tolerate PO)AdultIV
Acute asthma exacerbation#Prednisone Corticosteroid (pediatric) PediatricPrednisone1-2 mg/kg/day (max 60 mg) x3-10 daysAcute asthma exacerbationCorticosteroid (pediatric)PediatricPO
Acute asthma exacerbation#Dexamethasone Corticosteroid (preferred for adherence) AdultDexamethasone0.6 mg/kg IV or PO (max 16 mg); 2nd dose 24hr laterAcute asthma exacerbationCorticosteroid (preferred for adherence)AdultIV/PO
Acute asthma exacerbation#Magnesium sulfate High-dose magnesium (pediatric) PediatricMagnesium sulfate50 mg/kg/hr IV x4 hours (max 8000 mg total)Acute asthma exacerbationHigh-dose magnesium (pediatric)PediatricIV drip
Acute asthma exacerbation#Ketamine Induction for intubation / bronchodilator adjunct AdultKetamine1-2 mg/kg IV (induction); 1 mg/kg/hr drip (sedation)Acute asthma exacerbationInduction for intubation / bronchodilator adjunctAdultIV
Acute asthma exacerbation#Epinephrine Severe/life-threatening asthma AdultEpinephrine0.01 mg/kg (1:1000) SC or IM q20min x3 (max 0.5 mg)Acute asthma exacerbationSevere/life-threatening asthmaAdultSC/IM
Acute asthma exacerbation (peds)#Ipratropium Adjunctive anticholinergic; reduces admissions PediatricIpratropium0.25-0.5mg q20min x3 (with first 3 albuterol doses)Acute asthma exacerbation (peds)Adjunctive anticholinergic; reduces admissionsPediatricNebulized
Acute asthma exacerbation (peds)#Albuterol First-line bronchodilator PediatricAlbuterol2.5-5mg nebulized q20min x3 (intermittent) or 0.5mg/kg/hr continuous (max 15mg/hr)Acute asthma exacerbation (peds)First-line bronchodilatorPediatricNebulized
Acute asthma exacerbation (peds)#Magnesium sulfate Severe/refractory asthma; smooth muscle relaxation PediatricMagnesium sulfate25-50mg/kg (max 2g) IV over 20minAcute asthma exacerbation (peds)Severe/refractory asthma; smooth muscle relaxationPediatricIV
Acute asthma exacerbation (peds)#Prednisone Systemic corticosteroid alternative to dexamethasone PediatricPrednisone1-2mg/kg/day (max 60mg) in 1-2 divided doses x 3-5 daysAcute asthma exacerbation (peds)Systemic corticosteroid alternative to dexamethasonePediatricPO
Acute asthma exacerbation (peds)#Dexamethasone Systemic corticosteroid; PO and IV equally effective PediatricDexamethasone0.6mg/kg PO or IV (max 16mg); consider 2nd dose at 24-36hrAcute asthma exacerbation (peds)Systemic corticosteroid; PO and IV equally effectivePediatricPO/IV
Acute mountain sickness#Acetazolamide Mild AMS; speeds acclimatization via bicarb diuresis AdultAcetazolamide125-250mg BIDAcute mountain sicknessMild AMS; speeds acclimatization via bicarb diuresisAdultPO
Acute mountain sickness#Acetazolamide Moderate-severe AMS AdultAcetazolamide250mg BIDAcute mountain sicknessModerate-severe AMSAdultPO
Acute mountain sickness#Dexamethasone Moderate-severe AMS; symptomatic relief only, does not aid acclimatization AdultDexamethasone4mg q6hrAcute mountain sicknessModerate-severe AMS; symptomatic relief only, does not aid acclimatizationAdultPO
Acute pain management#Gabapentin Neuropathic pain adjuvant AdultGabapentin300 mg PO qhs (starting dose)Acute pain managementNeuropathic pain adjuvantAdultPO
Acute pain management#Indomethacin Non-opioid analgesic (NSAID) AdultIndomethacin25-50 mg PO q12h or 100 mg PR q24hAcute pain managementNon-opioid analgesic (NSAID)AdultPO/PR
Acute pain management#Naproxen Non-opioid analgesic (NSAID) AdultNaproxen250 mg PO q6-8h or 500-1000 mg PR q6-8hAcute pain managementNon-opioid analgesic (NSAID)AdultPO/PR
Acute pain management#Ketorolac Non-opioid analgesic (NSAID, parenteral) AdultKetorolac15-30 mg IV q6h or 30-60 mg IMAcute pain managementNon-opioid analgesic (NSAID, parenteral)AdultIV/IM
Acute pain management#Ibuprofen Step 1 - Mild pain (NSAID) AdultIbuprofen400-800 mg PO q6-8h PRNAcute pain managementStep 1 - Mild pain (NSAID)AdultPO
Acute pain management#Acetaminophen Step 1 - Mild pain (non-opioid) AdultAcetaminophen650 mg PO q4-6h PRN or 1000 mg PO q6h PRNAcute pain managementStep 1 - Mild pain (non-opioid)AdultPO
Acute pain management#Aspirin Step 1 - Mild pain (non-opioid) AdultAspirin650 mg PO q4-6h PRN or 1000 mg PO q6h PRNAcute pain managementStep 1 - Mild pain (non-opioid)AdultPO
Acute pain management#Codeine Step 2 - Moderate pain (mild opioid) AdultCodeine30-60 mg PO q3-4hAcute pain managementStep 2 - Moderate pain (mild opioid)AdultPO
Acute pain management#Hydrocodone Step 2 - Moderate pain (mild opioid) AdultHydrocodone5-10 mg PO q4-6h PRN (with acetaminophen 325 mg)Acute pain managementStep 2 - Moderate pain (mild opioid)AdultPO
Acute pain management#Oxycodone Step 2 - Moderate pain (mild opioid) AdultOxycodone5-10 mg PO q4-6h PRNAcute pain managementStep 2 - Moderate pain (mild opioid)AdultPO
Acute pain management#Tramadol Step 2 - Moderate pain (mild opioid) AdultTramadol50-100 mg PO q4-6hAcute pain managementStep 2 - Moderate pain (mild opioid)AdultPO
Acute pain management#Morphine Step 3 - Severe pain (1st line opioid) AdultMorphine0.1 mg/kg IV or 10 mg IM or 0.3 mg/kg PO; titrate 2-5 mg IV q5-10minAcute pain managementStep 3 - Severe pain (1st line opioid)AdultIV/IM/PO
Acute pain management#Butorphanol Step 3 - Severe pain (mixed agonist-antagonist) AdultButorphanol0.5-2.0 mg IV; average 2 mg q3-4hAcute pain managementStep 3 - Severe pain (mixed agonist-antagonist)AdultIV
Acute pain management#Hydromorphone Step 3 - Severe pain (opioid) AdultHydromorphone0.015 mg/kg IV or 1-2 mg IM; titrate 0.5-1.0 mg IV incrementsAcute pain managementStep 3 - Severe pain (opioid)AdultIV/IM
Acute pain management#Meperidine Step 3 - Severe pain (opioid, avoid if possible) AdultMeperidine1.0-1.5 mg/kg IV/IM; titrate 12.5-50 mg IV incrementsAcute pain managementStep 3 - Severe pain (opioid, avoid if possible)AdultIV/IM
Acute pain management#Fentanyl Step 3 - Severe pain (opioid, short-acting) AdultFentanyl1.0 mcg/kg IV; titrate 25-50 mcg IV q2-3minAcute pain managementStep 3 - Severe pain (opioid, short-acting)AdultIV
Acute respiratory distress syndrome#Cisatracurium Neuromuscular blockade to prevent barotrauma/vent dyssynchrony AdultCisatracurium0.15mg/kg load, then 1-3mcg/kg/minAcute respiratory distress syndromeNeuromuscular blockade to prevent barotrauma/vent dyssynchronyAdultIV
Acute respiratory distress syndrome#Methylprednisolone Pulse-dose steroids for early established severe ARDS (Meduri protocol) AdultMethylprednisolone1mg/kg load, then 1mg/kg/day (d1-14), taper over d15-28Acute respiratory distress syndromePulse-dose steroids for early established severe ARDS (Meduri protocol)AdultIV
Acute rheumatic fever#Aspirin Anti-inflammatory for carditis/arthritis PediatricAspirin50-100mg/kg/day PO divided q4-6hAcute rheumatic feverAnti-inflammatory for carditis/arthritisPediatricPO
Acute rheumatic fever#Prednisone Moderate-to-severe carditis PediatricPrednisone1-2mg/kg/day POAcute rheumatic feverModerate-to-severe carditisPediatricPO
Acute urinary retention#Tamsulosin Alpha-blocker for BPH-related retention (outpatient) AdultTamsulosin0.4mg QHSAcute urinary retentionAlpha-blocker for BPH-related retention (outpatient)AdultPO
Agitated or combative patient#Droperidol 1st line antipsychotic for acute agitation AdultDroperidol5 mg IM q5min x2Agitated or combative patient1st line antipsychotic for acute agitationAdultIM
Agitated or combative patient#Haloperidol Antipsychotic for acute agitation AdultHaloperidol5-10 mg IMAgitated or combative patientAntipsychotic for acute agitationAdultIM
Agitated or combative patient#Olanzapine Atypical antipsychotic for agitation AdultOlanzapine10 mg IMAgitated or combative patientAtypical antipsychotic for agitationAdultIM
Agitated or combative patient#Ziprasidone Atypical antipsychotic for agitation AdultZiprasidone20 mg IMAgitated or combative patientAtypical antipsychotic for agitationAdultIM
Agitated or combative patient#Lorazepam Benzodiazepine for agitation AdultLorazepam2 mg IV/IMAgitated or combative patientBenzodiazepine for agitationAdultIV/IM
Agitated or combative patient#Midazolam Benzodiazepine for agitation AdultMidazolam5 mg IMAgitated or combative patientBenzodiazepine for agitationAdultIM
Agitated or combative patient#Ketamine Rescue sedation for severe agitation AdultKetamine4-6 mg/kg IM or 1 mg/kg IVAgitated or combative patientRescue sedation for severe agitationAdultIM/IV
Akathisia#Benztropine Anticholinergic, first-line AdultBenztropine1-2mg IVAkathisiaAnticholinergic, first-lineAdultIV
Akathisia#Diphenhydramine Anticholinergic, first-line AdultDiphenhydramine50mg PO/IM/IVAkathisiaAnticholinergic, first-lineAdultPO/IM/IV
Aluminum phosphide poisoning#Magnesium sulfate Cardioprotective, may reduce mortality AdultMagnesium sulfate4g IV over 20min, then 6g over 12hr infusionAluminum phosphide poisoningCardioprotective, may reduce mortalityAdultIV
Aluminum phosphide poisoning#Sodium bicarbonate Correct metabolic acidosis AdultSodium bicarbonate1-2mEq/kg IV bolus, then infusion to maintain pH >7.2Aluminum phosphide poisoningCorrect metabolic acidosisAdultIV
Amanita mushrooms#N-Acetylcysteine Hepatoprotective, mortality benefit AdultN-Acetylcysteine150mg/kg IV over 15min, then 50mg/kg over 4hr, then 100mg/kg over 16hrAmanita mushroomsHepatoprotective, mortality benefitAdultIV
Amanita mushrooms#Penicillin G Inhibits amatoxin uptake AdultPenicillin G1 million units/kg/day IV divided q4hrAmanita mushroomsInhibits amatoxin uptakeAdultIV
Angioedema#Epinephrine Allergic/anaphylactic angioedema AdultEpinephrine0.3 mg IMAngioedemaAllergic/anaphylactic angioedemaAdultIM
Angioedema#Diphenhydramine Antihistamine (allergic angioedema) AdultDiphenhydramine50 mg IVAngioedemaAntihistamine (allergic angioedema)AdultIV
Angioedema#Icatibant Bradykinin B2 receptor antagonist (HAE/ACE-I angioedema) AdultIcatibant30 mg SCAngioedemaBradykinin B2 receptor antagonist (HAE/ACE-I angioedema)AdultSC
Angioedema#Tranexamic acid Bradykinin-mediated angioedema (e.g., ACE-I induced) AdultTranexamic acid1 g IV over 10 minAngioedemaBradykinin-mediated angioedema (e.g., ACE-I induced)AdultIV
Angioedema#Methylprednisolone Corticosteroid (allergic angioedema) AdultMethylprednisolone125 mg IVAngioedemaCorticosteroid (allergic angioedema)AdultIV
Angioedema#Glucagon If on beta-blockers and not responding to epinephrine AdultGlucagon1-5 mg IVAngioedemaIf on beta-blockers and not responding to epinephrineAdultIV
Angioedema#Ecallantide Kallikrein inhibitor (HAE) AdultEcallantide10 mg SC x3 at different sites (30 mg total)AngioedemaKallikrein inhibitor (HAE)AdultSC
Anticoagulant reversal for life-threatening bleeds#Idarucizumab Dabigatran reversal AdultIdarucizumab5g IVAnticoagulant reversal for life-threatening bleedsDabigatran reversalAdultIV
Anticoagulant reversal for life-threatening bleeds#Protamine Heparin/LMWH reversal AdultProtamine sulfate50mg IV (<8hr since last dose), 25mg (8-12hr)Anticoagulant reversal for life-threatening bleedsHeparin/LMWH reversalAdultIV
Anticoagulant reversal for life-threatening bleeds#Vitamin K Warfarin reversal with life-threatening bleed (INR >10) AdultVitamin K10mg IV over 30minAnticoagulant reversal for life-threatening bleedsWarfarin reversal with life-threatening bleed (INR >10)AdultIV
Antipsychotic toxicity#Diphenhydramine Dystonic reaction AdultDiphenhydramine25-50mg IV/IMAntipsychotic toxicityDystonic reactionAdultIV/IM
Antipsychotic toxicity#Benztropine Dystonic reaction, alternative AdultBenztropine1-2mg IV/IMAntipsychotic toxicityDystonic reaction, alternativeAdultIV/IM
Antipsychotic toxicity#Magnesium sulfate QTc >500ms AdultMagnesium sulfate2-4g IV over 10 minAntipsychotic toxicityQTc >500msAdultIV
Atrial fibrillation (main)#Apixaban Anticoagulation (NOAC) AdultApixaban5 mg BID (reduced: 2.5 mg BID if ≥2 of: age ≥80, wt ≤60 kg, Cr ≥1.5)Atrial fibrillation (main)Anticoagulation (NOAC)AdultPO
Atrial fibrillation (main)#Dabigatran Anticoagulation (NOAC) AdultDabigatran150 mg BID (reduced: 75 mg BID if CrCl 15-30)Atrial fibrillation (main)Anticoagulation (NOAC)AdultPO
Atrial fibrillation (main)#Edoxaban Anticoagulation (NOAC) AdultEdoxaban60 mg daily (reduced: 30 mg daily if CrCl 15-50 or wt ≤60 kg)Atrial fibrillation (main)Anticoagulation (NOAC)AdultPO
Atrial fibrillation (main)#Rivaroxaban Anticoagulation (NOAC) AdultRivaroxaban20 mg daily with evening meal (reduced: 15 mg daily if CrCl 15-50)Atrial fibrillation (main)Anticoagulation (NOAC)AdultPO
Atrial fibrillation (main)#Diltiazem Rate control (1st line CCB) AdultDiltiazem0.25-0.35 mg/kg IV (typical 20 mg), then 25 mg IV if needed; followed by 60-120 mg PO or dripAtrial fibrillation (main)Rate control (1st line CCB)AdultIV/PO
Atrial fibrillation (main)#Metoprolol Rate control (1st line beta-blocker) AdultMetoprolol5 mg IV q5min x3Atrial fibrillation (main)Rate control (1st line beta-blocker)AdultIV
Atrial fibrillation (main)#Digoxin Rate control (if hypotensive or advanced HF) AdultDigoxin500 mcg IV, then 250 mcg q4h x2 (total 1000 mcg digitizing dose)Atrial fibrillation (main)Rate control (if hypotensive or advanced HF)AdultIV
Atrial fibrillation (main)#Procainamide Rhythm control (Ottawa aggressive protocol) AdultProcainamide1 g IV over 60 min (Ottawa protocol); hold if SBP <100Atrial fibrillation (main)Rhythm control (Ottawa aggressive protocol)AdultIV
Atrial fibrillation (main)#Amiodarone Rhythm control (if hypotension or advanced HF) AdultAmiodarone150 mg IV over 10 min, then 1 mg/min x6h, then 0.5 mg/min x18hAtrial fibrillation (main)Rhythm control (if hypotension or advanced HF)AdultIV drip
Atrial fibrillation with RVR#Magnesium sulfate Adjunctive rate control AdultMagnesium sulfate2g over 1-5min; repeat after 15min if no response; then 1-2g/hr x 4hrAtrial fibrillation with RVRAdjunctive rate controlAdultIV
Atrial fibrillation with RVR#Diltiazem First-line rate control (CCB) AdultDiltiazem0.25mg/kg (max 20mg) IV over 2min; repeat 0.35mg/kg after 15min; drip 5-20mg/hrAtrial fibrillation with RVRFirst-line rate control (CCB)AdultIV
Atrial fibrillation with RVR#Metoprolol Rate control (beta-blocker) AdultMetoprolol5mg IV q5min x3Atrial fibrillation with RVRRate control (beta-blocker)AdultIV
Atrial fibrillation with RVR#Esmolol Rate control (beta-blocker); easily titratable AdultEsmolol0.5mg/kg bolus over 1min, then 50-200mcg/kg/minAtrial fibrillation with RVRRate control (beta-blocker); easily titratableAdultIV
Atrial fibrillation with RVR#Amiodarone Unstable AF; rate/rhythm control when other agents fail AdultAmiodarone150mg over 10min, up to 6 dosesAtrial fibrillation with RVRUnstable AF; rate/rhythm control when other agents failAdultIV
Atrial flutter#Procainamide Preexcited atrial flutter AdultProcainamide20-50 mg/min until arrhythmia controlledAtrial flutterPreexcited atrial flutterAdultIV
Atrial flutter#Diltiazem Rate control AdultDiltiazem2.5 mg/min until HR <100 (max 50 mg)Atrial flutterRate controlAdultIV
Atrial flutter#Amiodarone Rate control (alternative) AdultAmiodarone150 mg over 10 minAtrial flutterRate control (alternative)AdultIV
Benzodiazepine toxicity#Flumazenil Benzodiazepine antagonist (controversial) AdultFlumazenil0.2 mg IV, repeat q1minBenzodiazepine toxicityBenzodiazepine antagonist (controversial)AdultIV
Beriberi#Thiamine Thiamine replacement AdultThiamine50-100mg IV/IM daily x 7-14 days, then 10mg PO daily until recoveryBeriberiThiamine replacementAdultIV/IM
Beta-blocker toxicity#Calcium chloride Calcium supplementation AdultCalcium chloride1-3 g IV (10-20 mL 10% solution)Beta-blocker toxicityCalcium supplementationAdultIV
Beta-blocker toxicity#Insulin High-dose insulin euglycemic therapy AdultInsulin1 unit/kg IV bolus with D50, then 0.5-1 unit/kg/hr dripBeta-blocker toxicityHigh-dose insulin euglycemic therapyAdultIV/IV drip
Beta-blocker toxicity#Intralipid Lipid emulsion therapy AdultIntralipid1.5 mL/kg IV bolus of 20%, then 0.25 mL/kg/min for 30-60 minBeta-blocker toxicityLipid emulsion therapyAdultIV/IV drip
Beta-blocker toxicity#Glucagon Positive inotrope/chronotrope (acts independently of beta receptors) AdultGlucagon5 mg IV bolus over 1 min (adult); 50 mcg/kg (pediatric); repeat in 10 min if no response; then drip 2-5 mg/hrBeta-blocker toxicityPositive inotrope/chronotrope (acts independently of beta receptors)AdultIV/IV drip
Beta-blocker toxicity#Glucagon Positive inotrope/chronotrope (pediatric) PediatricGlucagon50 mcg/kg IV bolus; then 70 mcg/kg/hr dripBeta-blocker toxicityPositive inotrope/chronotrope (pediatric)PediatricIV/IV drip
Beta-blocker toxicity#Atropine Symptomatic bradycardia (initial) AdultAtropine0.5-1 mg IV q3-5min (max 3 mg)Beta-blocker toxicitySymptomatic bradycardia (initial)AdultIV
Body packing#Naloxone Opioid packet rupture AdultNaloxone2-5mg IV initially, repeat 2mg q5min until responsive; then continuous infusion at total response dose/hrBody packingOpioid packet ruptureAdultIV
COPD exacerbation#Hydrocortisone Corticosteroid (IV option) AdultHydrocortisone topical100-125 mg IV q6h x5 daysCOPD exacerbationCorticosteroid (IV option)AdultIV
COPD exacerbation#Methylprednisolone Corticosteroid (IV option) AdultMethylprednisolone125 mg IV daily (1-2 mg/kg)COPD exacerbationCorticosteroid (IV option)AdultIV
COPD exacerbation#Prednisone Corticosteroid (preferred, oral) AdultPrednisone60 mg PO x1, then 40 mg PO daily x5 daysCOPD exacerbationCorticosteroid (preferred, oral)AdultPO
Calcium channel blocker toxicity#Glucagon Adjunct for bradycardia/hypotension AdultGlucagon5 mg IV bolus q10min x2Calcium channel blocker toxicityAdjunct for bradycardia/hypotensionAdultIV
Calcium channel blocker toxicity#Calcium gluconate Calcium supplementation AdultCalcium gluconate3 g (30-60 mL of 10% solution) IV bolusCalcium channel blocker toxicityCalcium supplementationAdultIV
Calcium channel blocker toxicity#Calcium chloride Calcium supplementation (preferred, 3x calcium vs gluconate) AdultCalcium chloride1-3 g IV bolus (10-20 mL 10% solution), then 1 g IV q5min to BP effect; drip 10-50 mg/kg/hrCalcium channel blocker toxicityCalcium supplementation (preferred, 3x calcium vs gluconate)AdultIV/IV drip
Calcium channel blocker toxicity#Insulin High-dose insulin euglycemic therapy (best evidence) AdultInsulin1 unit/kg IV bolus with D50, then 0.5-1 unit/kg/hr drip (max 2 units/kg/hr)Calcium channel blocker toxicityHigh-dose insulin euglycemic therapy (best evidence)AdultIV/IV drip
Calcium channel blocker toxicity#Intralipid Lipid emulsion therapy AdultIntralipid1.5 mL/kg IV bolus of 20% lipid, then 0.25 mL/kg/minCalcium channel blocker toxicityLipid emulsion therapyAdultIV/IV drip
Calcium channel blocker toxicity#Atropine Symptomatic bradycardia AdultAtropine0.5-1 mg IV q2-3min (max 3 mg)Calcium channel blocker toxicitySymptomatic bradycardiaAdultIV
Calcium channel blocker toxicity#Atropine Symptomatic bradycardia (pediatric) PediatricAtropine0.02 mg/kg IV (min 0.1 mg)Calcium channel blocker toxicitySymptomatic bradycardia (pediatric)PediatricIV
Calcium channel blocker toxicity#Norepinephrine Vasopressor (agent of choice) AdultNorepinephrineStart 2 mcg/min, uptitrate rapidly to MAP ≥65Calcium channel blocker toxicityVasopressor (agent of choice)AdultIV drip
Cannabinoid hyperemesis syndrome#Diphenhydramine Adjunct with haloperidol AdultDiphenhydramine50mg IVCannabinoid hyperemesis syndromeAdjunct with haloperidolAdultIV
Cannabinoid hyperemesis syndrome#Haloperidol Antiemetic, first-line AdultHaloperidol5mg IV or IMCannabinoid hyperemesis syndromeAntiemetic, first-lineAdultIV/IM
Cannabinoid hyperemesis syndrome#Lorazepam Anxiolytic/antiemetic AdultLorazepam1-2mg IVCannabinoid hyperemesis syndromeAnxiolytic/antiemeticAdultIV
Carbamate poisoning#Atropine Antimuscarinic, first-line AdultAtropine1-2mg IV, double dose q5min until drying of secretionsCarbamate poisoningAntimuscarinic, first-lineAdultIV
Carbamate poisoning#Atropine Antimuscarinic, first-line PediatricAtropine0.02-0.05mg/kg IV (min 0.1mg), double q5min until drying of secretionsCarbamate poisoningAntimuscarinic, first-linePediatricIV
Carbamate poisoning#Pralidoxime Only if unknown agent or mixed OP/carbamate exposure AdultPralidoxime20mg/kg (max 2g) IV over 30min, then 8-10mg/kg/hr (max 650mg/hr)Carbamate poisoningOnly if unknown agent or mixed OP/carbamate exposureAdultIV
Carbamate poisoning#Diazepam Seizure control AdultDiazepam5-10mg IVCarbamate poisoningSeizure controlAdultIV
Carbamate poisoning#Diazepam Seizure control PediatricDiazepam0.2-0.5mg/kg IVCarbamate poisoningSeizure controlPediatricIV
Carbamate toxicity#Pralidoxime Cholinergic toxicity (oxime reactivator) AdultPralidoxime1-2 g IV over 15-30 min, then 8-10 mg/kg/hr infusion (or repeat bolus in 1 hr)Carbamate toxicityCholinergic toxicity (oxime reactivator)AdultIV
Carbamate toxicity#Pralidoxime Cholinergic toxicity (oxime reactivator) PediatricPralidoxime20-50 mg/kg IV, then 5-10 mg/kg/hr infusionCarbamate toxicityCholinergic toxicity (oxime reactivator)PediatricIV
Carbamate toxicity#Atropine Cholinergic toxicity antidote (muscarinic) PediatricAtropine0.02-0.05 mg/kg IV (min 0.1 mg), double q5minCarbamate toxicityCholinergic toxicity antidote (muscarinic)PediatricIV
Carbamate toxicity#Atropine Cholinergic toxicity antidote (muscarinic) AdultAtropine1-2 mg IV (double q5min until atropinization)Carbamate toxicityCholinergic toxicity antidote (muscarinic)AdultIV
Cesium toxicity#Magnesium sulfate First-line for QTc prolongation AdultMagnesium sulfate2g IV bolusCesium toxicityFirst-line for QTc prolongationAdultIV
Chloramine#Dexamethasone Airway inflammation AdultDexamethasone0.6mg/kg IV or PO (max 16mg)ChloramineAirway inflammationAdultIV/PO
Chloramine#Methylprednisolone Airway inflammation AdultMethylprednisolone125mg IV (adults); 2mg/kg IV (children)ChloramineAirway inflammationAdultIV
Chloramine#Albuterol Bronchospasm AdultAlbuterol2.5-5mg nebulized q20min or continuousChloramineBronchospasmAdultNebulized
Cholinergic crisis#Atropine Antimuscarinic, first-line AdultAtropine2-4mg IV q5min, titrate to resolution of bronchorrhea; then infusion at 10% of loading dose/hrCholinergic crisisAntimuscarinic, first-lineAdultIV
Cholinergic crisis#Pralidoxime Cholinesterase reactivator AdultPralidoxime20mg/kg (max 2g) IV over 30min, then 8-10mg/kg/hr (max 650mg/hr)Cholinergic crisisCholinesterase reactivatorAdultIV
Cholinergic crisis#Lorazepam Seizure control AdultLorazepam2-4mg IVCholinergic crisisSeizure controlAdultIV
Clonidine toxicity#Atropine Bradycardia AdultAtropine0.5-1 mgClonidine toxicityBradycardiaAdultIV
Clonidine toxicity#Naloxone CNS/respiratory depression reversal AdultNaloxone0.4-2 mg IV, may repeat up to 10 mgClonidine toxicityCNS/respiratory depression reversalAdultIV
Coarctation of the aorta#Furosemide CHF management PediatricFurosemide1-2mg/kg IVCoarctation of the aortaCHF managementPediatricIV
Coarctation of the aorta#Prostaglandin E1 Duct-dependent lesion, maintain PDA patency PediatricProstaglandin E10.1mcg/kg/min IV/IOCoarctation of the aortaDuct-dependent lesion, maintain PDA patencyPediatricIV/IO
Coarctation of the aorta#Dobutamine Inotropic support for CHF PediatricDobutamine5-10mcg/kg/min IVCoarctation of the aortaInotropic support for CHFPediatricIV
Coarctation of the aorta#Dopamine Inotropic support for CHF PediatricDopamine5-10mcg/kg/min IVCoarctation of the aortaInotropic support for CHFPediatricIV
Cocaine toxicity#Phentolamine Direct alpha-antagonist for refractory hypertension AdultPhentolamine2.5-5mg IVCocaine toxicityDirect alpha-antagonist for refractory hypertensionAdultIV
Cocaine toxicity#Diazepam First-line for agitation, seizures, and sympathetic excess AdultDiazepam5-10mg IV q5min PRN agitationCocaine toxicityFirst-line for agitation, seizures, and sympathetic excessAdultIV
Congenital heart disease#Prostaglandin E1 Duct-dependent lesions, maintain PDA patency PediatricProstaglandin E10.1mcg/kg/min IV/IOCongenital heart diseaseDuct-dependent lesions, maintain PDA patencyPediatricIV/IO
Congenital heart disease#Phenylephrine Tet spell (TOF), increase SVR PediatricPhenylephrine2-10mcg/kg/min IV infusionCongenital heart diseaseTet spell (TOF), increase SVRPediatricIV
Congenital heart disease#Propranolol Tet spell (TOF), relieves infundibular spasm PediatricPropranolol0.2mg/kg IVCongenital heart diseaseTet spell (TOF), relieves infundibular spasmPediatricIV
Congestive heart failure#Enalaprilat ACE inhibitor for afterload reduction AdultEnalaprilat0.004 mg/kg IV bolus or 1 mg IV drip over 2 hoursCongestive heart failureACE inhibitor for afterload reductionAdultIV
Congestive heart failure#Nitroprusside Afterload reduction (if HTN or NTG ineffective) AdultNitroprusside0.3 mcg/kg/min IV dripCongestive heart failureAfterload reduction (if HTN or NTG ineffective)AdultIV drip
Congestive heart failure#Furosemide Diuresis (hold if no fluid overload; give nitrates first) AdultFurosemideDouble home dose IV or up to 2.5x dose (e.g., if 40 mg PO daily → 40-100 mg IV)Congestive heart failureDiuresis (hold if no fluid overload; give nitrates first)AdultIV
Congestive heart failure#Dobutamine Inotrope (1st line for hypotensive HF) AdultDobutamine2-20 mcg/kg/min IV dripCongestive heart failureInotrope (1st line for hypotensive HF)AdultIV drip
Congestive heart failure#Milrinone Inotrope (if on beta-blockers) AdultMilrinone0.375-0.75 mcg/kg/min IV dripCongestive heart failureInotrope (if on beta-blockers)AdultIV drip
Congestive heart failure#Nitroglycerin Preload/afterload reduction (1st line for hypertensive HF) AdultNitroglycerin0.4 mg SL q5min x3; or IV drip start 10-20 mcg/min, titrate to BP (keep >95)Congestive heart failurePreload/afterload reduction (1st line for hypertensive HF)AdultSL/IV drip
Copper sulfate toxicity#Dimercaprol Chelation, first-line for severe AdultDimercaprol3-5mg/kg/dose IM q4hr x 2 days, then taper over 7-11 daysCopper sulfate toxicityChelation, first-line for severeAdultIM
Copper sulfate toxicity#Penicillamine Oral chelation AdultPenicillamine1-1.5g/day PO in 2-4 divided dosesCopper sulfate toxicityOral chelationAdultPO
... further results

Example: Drug Page Query — All Indications for Ketamine

 IndicationDoseContextRoutePopulation
Acute asthma exacerbation#Ketamine Induction for intubation / bronchodilator adjunct AdultAcute asthma exacerbation1-2 mg/kg IV (induction); 1 mg/kg/hr drip (sedation)Induction for intubation / bronchodilator adjunctIVAdult
Agitated or combative patient#Ketamine Rescue sedation for severe agitation AdultAgitated or combative patient4-6 mg/kg IM or 1 mg/kg IVRescue sedation for severe agitationIM/IVAdult
Ethanol withdrawal#Ketamine Adjunct for refractory withdrawal AdultEthanol withdrawal0.15-0.3 mg/kg/hr IV dripAdjunct for refractory withdrawalIV dripAdult
Excited delirium#Ketamine Chemical sedation for excited delirium AdultExcited delirium4-5 mg/kgChemical sedation for excited deliriumIMAdult
Procedural sedation#Ketamine Procedural sedation AdultProcedural sedation1-2 mg/kgProcedural sedationIVAdult
Procedural sedation#Ketamine Procedural sedation (IM) AdultProcedural sedation4-5 mg/kgProcedural sedation (IM)IMAdult
Procedural sedation#Ketamine Procedural sedation PediatricProcedural sedation1.5-2 mg/kgProcedural sedationIVPediatric
Procedural sedation#Ketamine Procedural sedation (IM) PediatricProcedural sedation4-5 mg/kgProcedural sedation (IM)IMPediatric
Procedural sedation#Ketamine Procedural sedation (IN) PediatricProcedural sedation3-6 mg/kgProcedural sedation (IN)INPediatric
Rapid sequence intubation#Ketamine Induction AdultRapid sequence intubation1-2 mg/kgInductionIVAdult
Rapid sequence intubation#Ketamine Induction (IM) AdultRapid sequence intubation3-4 mg/kgInduction (IM)IMAdult

Example: Drug Page Query — All Indications for Epinephrine

 IndicationDoseContextRoute
Acute asthma exacerbation#Epinephrine Severe/life-threatening asthma AdultAcute asthma exacerbation0.01 mg/kg (1:1000) SC or IM q20min x3 (max 0.5 mg)Severe/life-threatening asthmaSC/IM
Angioedema#Epinephrine Allergic/anaphylactic angioedema AdultAngioedema0.3 mg IMAllergic/anaphylactic angioedemaIM
Croup#Epinephrine Moderate-severe croup with stridor at rest PediatricCroup0.5 mL/kg of 1:1000 nebulized (max 5 mL); or 0.05 mL/kg racemic epi 2.25% (max 0.5 mL)Moderate-severe croup with stridor at restNebulized
Newborn resuscitation#Epinephrine Persistent bradycardia despite ventilation and compressions PediatricNewborn resuscitation0.01-0.03mg/kg (0.1-0.3mL/kg of 1:10,000) IV/IO q3-5minPersistent bradycardia despite ventilation and compressionsIV/IO
Pulseless arrest#Epinephrine Pulseless arrest AdultPulseless arrest1 mg q3-5 minPulseless arrestIV/IO
Pulseless arrest#Epinephrine Pulseless arrest (asystole/PEA) AdultPulseless arrest1 mg q3-5 minPulseless arrest (asystole/PEA)IV/IO
Sepsis (main)#Epinephrine 3rd line vasopressor AdultSepsis (main)1-20 mcg/min3rd line vasopressorIV drip
Vasopressors#Epinephrine 2nd/3rd line vasopressor AdultVasopressors1-10 mcg/min (0.01-0.1 mcg/kg/min), max 0.5 mcg/kg/min2nd/3rd line vasopressorIV drip
Vasopressors#Epinephrine Vasopressor/inotrope; consider in refractory shock AdultVasopressors0.01-0.5mcg/kg/minVasopressor/inotrope; consider in refractory shockIV
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