Oxygen toxicity: Difference between revisions

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===Ocular===
===Ocular===
*Generally only seen in infants
*Retinopathy of prematurity (retrolentar fibroplasia)
**Retinopathy of prematurity (retrolentar fibroplasia)
**Seen in premature infants
*In adults exposed to repeated toxic levels of oxygen, can get hyperoxic myopia, which resolves spontaneously<ref>Anderson B, Farmer JC. Hyperoxic myopia. Transactions of the American Ophthalmological Society. 1978;76:116-124.</ref>
*In adults exposed to repeated toxic levels of oxygen, can get hyperoxic myopia<ref>Anderson B, Farmer JC. Hyperoxic myopia. Transactions of the American Ophthalmological Society. 1978;76:116-124.</ref>
**Resolves spontaneously over several weeks


==Differential Diagnosis==
==Differential Diagnosis==

Revision as of 10:07, 4 March 2016

Background

  • Resulting from the harmful effects of breathing oxygen at elevated partial pressures

Clinical Features

Pulmonary

  • Tracheobronchial irritation → pleuritic chest pain, dyspnea and coughing[1]
  • Atelectasis
  • Diffuse alveolar damage → Pulmonary edema/ARDS

Central nervous system

  • Tunnel vision
  • Tinnitus
  • Nausea
  • Facial twitching
  • Irritability (personality changes, anxiety, confusion, etc.)
  • Seizure

Ocular

  • Retinopathy of prematurity (retrolentar fibroplasia)
    • Seen in premature infants
  • In adults exposed to repeated toxic levels of oxygen, can get hyperoxic myopia[2]
    • Resolves spontaneously over several weeks

Differential Diagnosis

Diving Emergencies

Diagnosis

  • Clinical diagnosis

Management

  • Removal from high partial pressure of oxygen, if possible

Disposition

  • Admit

See Also

External Links

References

  1. Thomson L, Paton J. Oxygen toxicity. Paediatr Respir Rev. 2014 Jun;15(2):120-3.
  2. Anderson B, Farmer JC. Hyperoxic myopia. Transactions of the American Ophthalmological Society. 1978;76:116-124.