Arthritis

DDX By Number of Affected Joints

Monoarticular arthritis

Algorithm for Monoarticular arthralgia

• Acute osteoarthritis
• Avascular necrosis
• Crystal-induced (Gout, Pseudogout)
• Gonococcal arthritis, arthritis-dermatitis syndrome
• Nongonococcal septic arthritis
• Lyme disease
• Malignancy (metastases, osteochondroma, osteoid osteoma)
• Reactive poststreptococcal arthritis
• Trauma-induced arthritis
  • Fracture
  • Ligamentous injury
  • Overuse
• Avascular necrosis
• Decompression sickness
• Spontaneous osteonecrosis
• Hemorrhagic (e.g. hemophilia, systemic anticoagulation
• Seronegative spondyloarthropathies (ankylosing spondylitis, IBD, psoriatic arthritis, reactive arthritis
• RA, SLE
• Sarcoidosis, amyloidosis
• Periarticular pathology
  • Cellulitis
  • Tendonitis
  • Bursitis
• Transient (Toxic) Synovitis (Hip)
• Slipped Capital Femoral Epiphysis (SCFE)
• Legg Calve Perthes Disease

Oligoarthritis

1. Lyme Disease
2. Reactive arthritis (Reiter syndrome)
3. Ankylosing spondylitis
4. Gonococcal arthritis
5. Rheumatic Fever

Polyarthritis

1. Rheumatoid arthritis
2. SLE
3. Viral arthritis
4. Osteoarthritis (chronic)
5. Serum Sickness
6. Serum sickness–like reactions
7. Reactive Arthritis (Poststreptococcal)
8. Juvenile Idiopathic Arthritis

DDX For Migratory Pattern

1. Gonococcal arthritis
2. Acute Rheumatic Fever
3. Lyme Disease
4. Viral arthritis
5. SLE

See Also

• Arthrocentesis
• Diagnosis by Body Part (Main)

Source

• Tintinalli